Kawasaki disease causes a prolonged fever that's associated with damage to the heart and blood vessels. The cause is unknown but it's thought that a virus or bacterial infection may be responsible.
The symptoms of Kawasaki disease appear in phases. The first symptom is a fever that lasts at least five days. In the early stages it's difficult to distinguish the illness from a heavy cold.
Within a couple of days of the fever arising, conjunctivitis of both eyes and painful swollen neck glands appear.
After a few more days, a blotchy pink rash may appear on the trunk and genital area, the lips may become dry, red, cracked and swollen, the tongue becomes red and swollen like a strawberry, and the palms of the hands and the soles of the feet become swollen and purple-red in colour.
Asian and Afro-Caribbean people are more likely to develop Kawasaki disease, and boys are affected more often than girls. About one in five children affected will suffer heart damage as a result of the disease.
It's not currently possible to prevent Kawasaki disease, which is fatal for about one in 50 children affected.
Prompt treatment reduces the risk of potentially life-threatening heart-related complications. Treatment is usually with intravenous gammaglobulin (purified antibodies). High-dose aspirin is also given to reduce the risk of coronary artery aneurysms.